Coronavirus: Thread

Sun Sep 26 03:15:55 PDT 2021

https://indianexpress.com/article/cities/lucknow/uttar-pradesh-government-says-ivermectin-helped-to-keep-deaths-low-7311786/

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0247163
https://www.medrxiv.org/content/10.1101/2021.01.05.21249310v1
https://journals.sagepub.com/doi/pdf/10.1177/03000605211013550
https://poseidon01.ssrn.com/delivery.php?ID=541021002118114122091103085016081089109025032011016032119087102076096096025065092106001060102005041111018117099069094085119127042034007076000101066091084118012028030084017057102119113099099121007081069085089119026020010091094005103012001080000087113094&EXT=pdf&INDEX=TRUE
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816625/
https://ejmo.org/pdf/A%20Comparative%20Study%20on%20IvermectinDoxycycline%20and%20HydroxychloroquineAzithromycin%20Therapy%20on%20COVID19%20Patients-16263.pdf
https://www.ijidonline.com/article/S1201-9712(20)32506-6/fulltext
https://clinicaltrials.gov/ct2/results?term=ivermectin&cond=covid%2C+covid19%2C+covid+19&Search=Apply&age_v=&gndr=&type=&rslt=

The NIH, CDC, WHO and FDA have all recommended dexamethasone - a
corticosteroid which has shown efficacy in the treatment of severe
covid. It's also a commonly used drug to treat allergies in horses.

The difference? One can be used to treat billions of mild-moderate
cases - or as a prophylactic, while the other has a much more narrow
use - those suffering from severe Covid.

As Twitter user @DoRtChristians notes: "The FDA recently told the
public not to take life-saving Ivermectin because "you're not a
horse""

Ivermectin

This widely prescribed anti-parasitic which is also used in horses has
shown massive efficacy worldwide in the treatment of mild and moderate
cases of Covid-19, plus as a prophylactic. India's Uttar Pradesh
province, with a population of over 200 million, says that widespread
early use of Ivermectin 'helped keep positivity [and] deaths low.'
(source, May 12th)

Separately, there have been several studies funded by the Indian
government, primarily conducted through their largest govt. public
medical university (AIIMS).

    Role of ivermectin in the prevention of SARS-CoV-2 infection among
healthcare workers in India: A matched case-control study (source)

    Conclusion: Two-dose ivermectin prophylaxis at a dose of 300 μg/kg
with a gap of 72 hours was associated with a 73% reduction of
SARS-CoV-2 infection among healthcare workers for the following month.

    Ivermectin as a potential treatment for mild to moderate COVID-19
– A double blind randomized placebo-controlled trial (source)

    Conclusion: There was no difference in the primary outcome i.e.
negative RT-PCR status on day 6 of admission with the use of
ivermectin. However, a significantly higher proportion of patients
were discharged alive from the hospital when they received ivermectin.

    Clinical Research Report Ivermectin in combination with
doxycycline for treating COVID-19 symptoms: a randomized trial
(source, double-blind randomized, peer-reviewed)

    Discussion: In the present study, patients with mild or moderate
COVID-19 infection treated with ivermectin in combination with
doxycycline generally recovered 2 days earlier than those treated with
placebo. The proportion of patients responding within 7 days of
treatment was significantly higher in the treatment group than in the
placebo group. The proportions of patients who remained symptomatic
after 12 days of illness and who experienced disease progression were
significantly lower in the treatment group than in the placebo group.

Here are more human studies from other countries on the 'horse dewormer':

Peru:

    Sharp Reductions in COVID-19 Case Fatalities and Excess Deaths in
Peru in Close Time Conjunction, State-By-State, with Ivermectin
Treatments (source, peer-reviewed, University of Toronto, Universidad
EAFIT)

    For the 24 states with early IVM treatment (and Lima), excess
deaths dropped 59% (25%) at +30 days and 75% (25%) at +45 days after
day of peak deaths. Case fatalities likewise dropped sharply in all
states but Lima

Spain:

    The effect of early treatment with ivermectin on viral load,
symptoms and humoral response in patients with non-severe COVID-19: A
pilot, double-blind, placebo-controlled, randomized clinical trial
(source, University of Barcelona, peer-reviewed)

    Findings: Patients in the ivermectin group recovered earlier from
hyposmia/anosmia (76 vs 158 patient-days; p < 0.001).

Bengladesh:

    A Comparative Study on Ivermectin-Doxycycline and
Hydroxychloroquine-Azithromycin Therapy on COVID-19 Patients (source -
peer reviewed, though not govt funded)

    Conclusion: According  to  our  study,  the
Ivermectin-Doxycycline combination therapy has better symptomatic
relief, shortened recovery duration, fewer adverse effects, and
superior patient compliance compared to the
Hydroxychloroquine-Azithromycin combination. Based on this  study's
outcomes,  the  Ivermectin-Doxycycline  combination  is  a  superior
choice  for  treating  patients  with  mild to moderate COVID-19
disease.

    A five-day course of ivermectin for the treatment of COVID-19 may
reduce the duration of illness (source, peer-reviewed double blind
randomized, though small sample size)

    Discussion: A 5-day course of ivermectin resulted in an earlier
clearance of the virus compared to placebo (p = 0.005), thus
indicating that early intervention with this agent may limit viral
replication within the host. In the 5-day ivermectin group, there was
a significant drop in CRP and LDH by day 7, which are indicators of
disease severity.

Meanwhile, There are currently 76 ongoing or completed clinical trials
on Ivermectin around the world. Below are the results of 32 which have
been completed. One can visit ivermeta.com and dig down on any of
these / read the entire study. The site recommends Ivermectin in
conjunction with vaccines to confer the best protection against
Covid-19, however we'll leave that to you and your doctor to discuss.
Screenshot, http://ivermeta.com/

Why does Ivermectin, a 'horse dewormer' work? For starters, it's a
protease inhibitor. Interestingly, Pfizer's 2x/day Covid-19
prophylactic they're trialing right now is also a protease inhibitor.

Yet doctors who advocate for Ivermectin are ridiculed by the media
(more here and here and here).

The MSM swarmed over 'horse paste overdoses'  for weeks after a
handful cases nationwide (and no deaths) - including an outright lie
amplified by Rolling Stone which they were forced to correct after the
hospital in question denied the claim.

Meanwhile, the likes of Maddow, Don Lemon and Chris Hayes jumped right
on the propaganda bandwagon - with Maddow promoting the debunked ER
story in a tweet she refuses to delete - and Twitter refuses to censor
for misinformation.

Why would any doctor put their career on the line to publicly advocate
for ivermectin when this is the result?

Per Google (via Wedgewood pharmacy): "Dexamethasone commonly is used
in horses to treat allergic reactions such as respiratory allergies,
chronic obstructive pulmonary disease (heaves), hives, itching and
inflammatory diseases including arthritis."

But, but...

    You are not a horse. You are not a cow. Seriously, y'all. Stop it.
https://t.co/TWb75xYEY4
    — U.S. FDA (@US_FDA) August 21, 2021

We can only assume that because official bodies are recommending
dexamethasone - and because it's used in severe covid - a much smaller
fraction of those looking at ivermectin as a prophylactic and
early-stage treatment, the transitive properties of media outrage over
people taking a 'horse medication' don't apply.